KMID : 0359720180360010019
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Journal of the Korean Neurological Association 2018 Volume.36 No. 1 p.19 ~ p.21
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Steroid Non-responsive Hashimoto¡¯s Encephalopathy Improved by Rituximab
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Jang Seong-Hwa
Moon Hye-Jin Cho Yong-Won
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Abstract
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Hashimoto¡¯s encephalopathy is a rare autoimmune disease, with symptoms of encephalopathy and high titers of serum anti-thyroid antibodies. Current diagnostic criteria include corticosteroid responsiveness, but in some cases, they are refractory to corticosteroids. In steroid non-responders, other immunomodulatory therapies could be applied. Recently, Rituximab is reported as a safe and effective treatment for Hashimoto¡¯s encephalopathy. We report a 50-year-old woman with Hashimoto¡¯s encephalopathy presented with confusion and catatonia who was refractory to corticosteroid and immunoglobulin but effectively treated with rituximab.
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KEYWORD
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Encephalopathy, Thyroid hormones, Rituximab, Glucocorticoids
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